Ruthanne

Ace-031, also known as ACVR2B, is a soluble form of activin type IIB receptor, which is an inhibitor of myostatin and other naturally occurring proteins that limit muscle growth. This compound was genetically developed to bind to myostatin before it can attach to its receptor and halt muscle growth. The two Biopharma companies that worked on this compound are Acceleron and Shire.Myostatin is a hormone in our bodies that signals muscles to stop growing and replicating. Therefore, when you inhibit, or block myostatin, muscles will be able to grow bigger and you will become stronger. Imagine being able to block myostatin and continue to grow muscle indefinitely – you would be able to become like a super hero.Even a slight decrease in myostatin would result in a dramatic increase in muscle mass, but it would also mean you would need more food to feed those muscles as well. Another problem is that our heart would continue growing, since it is a muscle, and over time this could lead to heart failure due to having this organ work too hard. Besides, in the long run, an unhealthy heart will definitely hurt your gains. Furthermore, you could also argue that your stomach would grow as well because you can’t control what muscles get affected or not. For instance, certain muscles might grow bigger than others. For example, you can have a 50% increase in your glutes and only 20% in your delts.PEPTIDE PROFILES Steve SmiSteve Smi 3 years ago No Comments 16,796 views 5 likes
Ace-031

Save
Ace-031, also known as ACVR2B, is a soluble form of activin type IIB receptor, which is an inhibitor of myostatin and other naturally occurring proteins that limit muscle growth. This compound was genetically developed to bind to myostatin before it can attach to its receptor and halt muscle growth. The two Biopharma companies that worked on this compound are Acceleron and Shire.

ace-031 bottle

Fig 1. Ace-031 Bottle

Table of Contents
1 What is myostatin?
2 Side Effects
3 Human studies
4 Fat Loss
5 FSH effects
6 Dosages
7 Half Life
8 Forums
What is myostatin and why do bodybuilders want to stop it?

Myostatin is a hormone in our bodies that signals muscles to stop growing and replicating. Therefore, when you inhibit, or block myostatin, muscles will be able to grow bigger and you will become stronger. Imagine being able to block myostatin and continue to grow muscle indefinitely – you would be able to become like a super hero.

Negatives aspects and side effects

Even a slight decrease in myostatin would result in a dramatic increase in muscle mass, but it would also mean you would need more food to feed those muscles as well. Another problem is that our heart would continue growing, since it is a muscle, and over time this could lead to heart failure due to having this organ work too hard. Besides, in the long run, an unhealthy heart will definitely hurt your gains. Furthermore, you could also argue that your stomach would grow as well because you can’t control what muscles get affected or not. For instance, certain muscles might grow bigger than others. For example, you can have a 50% increase in your glutes and only 20% in your delts.In the different studies that were conducted, subjects experienced a reduction in leptin concentration and boosted adiponectin, which is a ‘good fat’ hormone. Hence, perhaps Ace-031 does really contribute to fat loss. Another study showed an increase in alkaline phosphatase in the blood and reduced collagen telopeptide; this may mean it also helps strengthening the bones.

Human studies

In one human study, overweight females were given a one time dose of 250 milligrams (mg) of Ace 031. As a result, after a month their muscles in the thighs grew over a pound. What’s more, their lean body mass increased 3%, which is quite a result.

However, in another study done on young boys with muscle dystrophy, the test subjects ended up having gum and nose bleeding. Unfortunately, both Shire and Acceleration eventually abandoned their partnership, and since 2013 no further development has been conducted. Since then, you can find Ace-031 being sold as research chemicals on various websites, but no trusted brand has come out selling it yet.