Andarine (S4) is a SARM (selective androgen receptor modulator) which has been abandoned during clinical trials. It was developed by…
Andarine (S4) is a SARM (selective androgen receptor modulator) which has been abandoned during clinical trials. It was developed by the pharmaceutical company GTx, with the hopes it would be used to treat benign prostatic hypertrophy (enlarged prostate), without the nasty sides of drugs like finasteride. Although not the strongest SARM (selective androgen receptor modulator) on paper, it still has good effects on strength, lean muscle, and preventing muscle wasting. Due to this, weightlifters have discovered it the past 5-10 years, and have started utilizing it to help them achieve their fitness goals.Andarine (S4) works by binding to androgen receptors, selectively choosing muscle and bone, instead of attacking sex organs like anabolic steroids will. It alters gene expression, causing a boost in protein synthesis and anabolism in the body. By all measured guestimates, Andarine (S4) has about 35% of the binding affinity of straight testosterone. Unlike testosterone, it will not convert to dihydrotestosterone or estrogen. Not only that, but it was developed because it worked at blocking dihydrotestosterone (DHT) from binding to the prostate receptors. (more on this later)
Andarine (S4) can be used when bulking, cutting, strength re composition, or just for general wellness. If you use it solo at 50mgs per day you will notice a modest boost in the gym when it comes to strength, lean mass, and fat burning. Here are the best ways to use it for your goals:
hose who want to bulk can stack 50mgs per day of Andarine (S4), with 10mgs a day of RAD140 (Testolone), combined with an increased calorie diet. A typical cycle would be 8-12 weeks.
You can push harder in the gym when it comes to strength by combining 50mgs per day of Andarine (S4) with 10mgs a day Ligandrol (LGD-4033). Users usually report good strength gains after 2-3 weeks.
On paper, you might not assume Andarine (S4) would be great for cutting. But surprisingly, it is very effective especially when stacking 25mgs with 20mgs of Cardarine (GW501516). Users report very good results after 12 weeks on this stack.
Andarine (S4) can be very effective during a recomposition, which means you can lose fat and gain muscle at the same time. Users will stack 50mgs of Andarine (S4), with 25mgs a day of Ostarine Ostabolic (MK2866) + 20mgs a day of Cardarine (GW501516). Combine these three compounds with a caloric deficit and watch the fat melt off without losing muscle. Users will run this cycle for 8-12 weeks.
For those who simply want better mood and greater overall well being, use 25mgs of Andarine (S4) by itself for 8-12 weeks.